GUINEA PIG APOLIPOPROTEIN C-II: EXPRESSION IN E. COLI, FUNCTIONAL STUDIES OF RECOMBINANT WILD-TYPE AND MUTATED VARIANTS, AND DISTRIBUTION ON PLASMA LIPOPROTEINS

Guinea pig apolipoprotein C-II (apoC-II) lacks four amino acid residues in the amino-terminal, lipid-binding part compared to apoC-II from other mammalian species (Andersson et al.1991.J.Biol.Chem.266: 4074-4080).To explore whether this structural difference explains the low ability of guinea pig plasma to activate lipoprotein lipase in vitro, we h

The contractual mechanism of the federal relations regulation is fixed in the constitutional norms.However, the implementation practice for almost a quarter of a century indicates ambiguous tendencies.The paper analyzes the problems of concluding and implementing agreements on the distribution of powers and subject matters between the public author

On October 19, 2020, the Mw7.6 Sand Point earthquake struck south of the Shumagin Islands in Alaska.Moment tensors indicate the earthquake was primarily strike-slip, yet the event produced an enigmatic tsunami that was larger and more widespread than expected for an earthquake of that magnitude and mechanism.Using a suite of hydrodynamic, seismic,

BACKGROUND: Forecasting the effects of global changes on high altitude ecosystems requires an understanding of the long-term relationships between biota and forcing factors to identify resilience thresholds.Fire is a crucial forcing factor: both fuel build-up from land-abandonment in European mountains, and more droughts linked to global warming ar